This study, however, failed to detect the significant increase of miR-200b expression in the serum of OC patients as a function of the disease progression; also, no correlation was found between the miR-200b expression and the level of CA-125, age, tumour grade, tumour size, menopausal status, haemoglobin concentration or absence of pregnancy [57]. This evidence concerns the gene MUC16 and neoplasm.