Chang et al. reported that SP-A +186A/G and SP-B 1580C/T polymorphisms results in the elevated risk of preterm NRDS; on the other hand, polymorphisms of SP-B –18A/C, SP-D Met11 ThrT/C, and Ala160 ThrG/A genes are not associated to the risk of NRDS (Chang et al., 2016). Here, SFTPB is linked to newborn respiratory distress syndrome.