As shown in Figure 3B, A549 and H1650 cells with downregulation of ATG5 and BA treatment exhibited a notable decrease in the LC3II level and increase in the cleaved PARP level when compared with the BA-treated cells, indicating that autophagy inhibition enhances BA-induced apoptosis in NSCLC cells. This evidence concerns the gene ATG5 and non-small cell lung carcinoma.