TNF and Jaundice: There were cured jaundice, weight loss, liver enlargement, microscopy (i.e., piecemeal necrosis, focal lytic necrosis, apoptosis and focal inflammation, and disturbed cell proliferation (Ki-67-staining), cytoskeletal structure in the hepatic stellate cell (α-SMA staining), collagen presentation (Mallory staining), and biochemistry presentation (Sever et al., 2019), and counteracted the increased NOS3 expression, interleukin (IL)-6, tumor necrosis factor (TNF)-α, and IL-1β levels.