Fibroblast growth factor receptors (FGFR1-4) are tyrosine kinase receptors (TKIs) associated to cell survival, migration, and angiogenesis13,14, and FGFR1 activation by FGF in an autocrine loop can drive tumorigenesis of multiple tumor types, including lung cancer15–17. The gene discussed is FGFR1; the disease is neoplasm.