Asparagine and PRIMA-1 activity (area under the curve (AUC)) did not correlate (Fig. S3F), but interestingly, aspartate was inversely correlated to PRIMA-1 activity in 22 ALL cell lines in the DepMap analysis (Fig. S3G) (r = −0.5, p = 0.03). This evidence concerns the gene PRIMA1 and acute lymphoblastic leukemia.