Association between DADS phenotype and IgM paraprotein was also recently confirmed in a study that has investigated the frequency and role of comorbidities in a large cohort of CIDP patients and found that 12.5% of the patients with DADS had an IgM monoclonal gammopathy (versus 5.5% of the patients with typical CIDP) [48▪▪]. Here, CD40LG is linked to chronic inflammatory demyelinating polyradiculoneuropathy.