In addition, as the expression of NUP37 was highly positively correlated with the genes encoding PD‐L1 (CD274) and PD‐L2 (PDCD1LG2), it is more importantly that PD‐L1 and PD‐L2 are an immune checkpoint inhibitor in gliomas. This evidence concerns the gene PDCD1LG2 and central nervous system cancer.