Among UTUC patients compared to all high PD-L1 expressors, there was a trend towards a less favorable HR for death, although not statistically significant, with atezolizumab treatment relative to chemotherapy at a HR of 0.81 (95% CI 0.59-1.10) among all high PD-L1 expressors, a HR of 1-32 (95% CI 0.50-3.48) among renal primary patients, and a HR of 0.92 (95% CI 0.36-2.34) among ureter primary patients [27]. This evidence concerns the gene CD274 and renal pelvis/ureter urothelial carcinoma.