TRPV4 and central nervous system cancer: TRPV4 plays an oncogenic role in breast cancer, endometrial cancer, gastric cancer, oral squamous cell carcinoma, and COAD (Arbabian et al., 2020; Azimi et al., 2020; Fujii et al., 2020; Li et al., 2020; Wang et al., 2020) and a suppressor gene role in glioma (Huang et al., 2021).