For paired tumors and normal tissues in TCGA, TRPV4 was overexpressed in BLCA, CESC, CHOL, COAD, ESCA, LUSC, pheochromocytoma/paraganglioma (PCPG), and STAD (Figures 2A–H), while low TRPV4 expression was observed in LIHC, PRAD, breast invasive carcinoma (BRCA), kidney chromophobe (KICH), and KIRP (Figures 2I–M). This evidence concerns the gene TRPV4 and hereditary pheochromocytoma-paraganglioma.