In our analysis, CCL5, CCL19, CCL21, CXCR5, and CXCL2 were upregulated in AKI, which was consistent with that reported in previous studies (Sanz et al., 2010; Winterberg et al., 2013; Wohlfahrtova et al., 2015; Sobbe et al., 2020). This evidence concerns the gene CCL21 and acute kidney injury.