It was reported that BRMG increases the level of IL8, while decreases the levels of several interleukins (IL-1β, IL-2, IL-4, IL-6, and IL-12), tumor necrosis factor (TNF)-alpha, interferon-gamma (IFN-γ), and active soluble fas-ligand (sFasL) levels, thereby maintaining the effective optimal defense against hyper-inflammation-free viral infections (87). Here, TNF is linked to viral infectious disease.