BATF3 and neoplasm: IFN regulatory factor 8 (Irf8) (Guilliams et al., 2016) and basic leucine zipper transcriptional factor ATF-like 3 (Batf3) (Poulin et al., 2012; Grajales-Reyes et al., 2015) are critical transcriptional factors in the development of cDC1s and are essential for tumor rejection (Theisen et al., 2019).