Although this study demonstrated significantly higher expression of FADD in HSCC tissue than in paraneoplastic tissue, the expression level was not statistically different in terms of the key patient symptoms such as primary site, T staging, N staging, the presence of lymph node metastasis, and degree of tumor differentiation, or whether the patient was a smoker or non-smoker. The gene discussed is FADD; the disease is metastatic malignant neoplasm in the lymph nodes.