By using enzyme linked immunosorbent assay (ELISA) and Westernblot (WB) as detection methods, MOG-Ab have been found in patients with other neurological disorders including multiple sclerosis, stroke and polyneuropathy as well as in viral (HSV, EBV) or autoimmune encephalitis (anti-NMDAR) several years ago. The gene discussed is MOG; the disease is nervous system disorder.