IL6 and Hyperglycemia: It has been suggested that the antidiabetic activity of fucoxanthin is associated with regulation of adipocytokine secretion, such as tumor necrosis factor‐α (TNF‐α) and interleukin 6 (IL‐6) and also modulation of monocyte chemoattractant protein‐1 (MCP‐1) mRNA expression in white adipose tissue (WAT), leading to prevention of hyperglycemia in a type 2 diabetes (Hosokawa et al., 2010; Maeda et al., 2009).