Another study further indicated that T2DM risk attributed to BMI could be influenced by liver aminotransferase: in group of high levels of both AST and ALT and in group of high level of either AST or ALT, high BMI was independently associated with diabetes incidence, and in group of high levels of both AST and ALT, odds ratio was relatively higher than that in group of high levels of either AST and ALT; While in group of low levels of both AST and ALT, high BMI was not an independent risk factor for diabetes [25]. This evidence concerns the gene GPT and type 2 diabetes mellitus.