From two pairs of matched breast cancer samples, we found that some of the detected CNVs contained some genes that were related to breast cancer, such as PDZK1 (Kim et al., 2013), XRCC4 (Allen-Brady et al., 2006), Fbxl17 (Mason et al., 2020), ITGBL1 (Li et al., 2015), RORA (Taheri et al., 2017), BAGE (Fujie et al., 1997), AMOTL1 (Couderc et al., 2016), RAP80 (Osorio et al., 2009), PIWIL4 (Wang et al., 2016), CSE1L (Behrens et al., 2001), and USP18 (Tan et al., 2018). The gene discussed is PIWIL4; the disease is breast carcinoma.