TLR2 and Behcet disease: Candidate gene studies have reported that maternal herpes simplex virus 2 (HSV-2) interactions with GRIN2B increase risk of SZ (Demontis et al., 2011), and for BD, toll-like receptor 2 (TLR2) polymorphisms reportedly interact with T. gondii infection to increase risk (Oliveira et al., 2016).