POMC and post-traumatic stress disorder: In addition, PTSD-exposed mice also showed decreased gene expression of Pomc in the ARC compared with control mice (Figure 8D, Student’s t-test, t = 3.416, p < 0.01, 18 d.f.), but no differences were observed in both control (Figure 8E, Two-way ANOVA, CBD: F(1,38) = 0.561, p = 0.459; STR: F(1,38) = 0.158, p = 0.693; CBD x STR: F(1,38) = 2.859, p = 0.100) and PTSD-like mice (Figure 8F, Two-way ANOVA; CBD: F(1,37) = 0.0340, p = 0.855; STR: F(1,37) = 0.233, p = 0.632; CBD x STR: F(1,37) = 0.0370, p = 0.849) after CBD and/or STR administration.