CNR2 and post-traumatic stress disorder: In addition, in the PTSD-like group CBD treatment decreased while STR increased Cnr2 gene expression (Figure 9F, Two-way ANOVA, CBD: F(1,39) = 4.281, p < 0.05; STR: F(1,39) = 17.287, p < 0.001; CBD x STR: F(1,39) = 0.179, p = 0.675).