CRH and post-traumatic stress disorder: In the PTSD-like mice group, Two-way ANOVA revealed that STR reduced the gene expression of Crf, achieving a more pronounced reduction when combined with CBD (Figure 8C, Two-way ANOVA, CBD: F(1,38) = 0.733, p = 0.398; STR: F(1,38) = 8.885, p < 0.01; CBD x STR: F(1,38) = 4.246, p < 0.05).