TNFα and IL6 are up-regulated in many inflammatory diseases, such as rheumatoid arthritis (van Schouwenburg et al., 2013; Pandolfi et al., 2020), inflammatory lung diseases (Malaviya et al., 2017) and tumors (Balkwill, 2006; Jones and Jenkins, 2018). Here, IL6 is linked to rheumatoid arthritis.