NLGN3 and cystic fibrosis: Whereas the amplitudes of EPSCs for CF-mono and for CF-multi-S were similar between the two genotypes, those for CF-multi-W were significantly larger in NLGN3-R451C mutant mice than in wild-type mice (Figure 1D), which appeared to be the basis for the elevated disparity ratio in NLGN3-R451C mutant mice.