The former negatively regulates the IFN production in response to an infection mediated by RNA virus (Xing et al. 2018), while the latter is mainly associated with neutralization of the virus, operating during both the early and the late stages of the infection (Mallery et al. 2010; Vaysburd et al. 2013; Foss et al. 2019). This evidence concerns the gene IFNA1 and infection.