Interestingly, by analyzing a patient cohort being administered chemotherapy in the GSE62254 dataset, we noticed that the significant correlation between poor survival and elevated CRIP1 expression was affected by the transcriptional abundance of BRCA2 but not that of RAD51 (Fig. 4O), which presents further evidence that the impact of CRIP1 on the chemotherapeutic benefits of GC patients depends on a BRCA2-mediated HR repair process. The gene discussed is BRCA2; the disease is gastric cancer.