Our data identified several novel lncRNA transcripts including one of the most significantly upregulated, SNHG5, while SNHG16 was found to be part of a regulatory circuit involving miR-124-3p, we found SNHG5 to interact with miR-132-3p (Fig. 7a), which has previously been reported to affect cell proliferation, metastasis and migration of CRC through regulating interaction with CREB542. Here, SNHG16 is linked to colorectal carcinoma.