LOX and neoplasm: By recording the fluorescence of Cy5.5 covalently labeled on the LOX of HLCaP NRs using an IVIS in vivo fluorescence imaging system, it was semiquantitatively shown that ~25% of HLCaP NRs in the presence of such adhesive glue remained at the tumor site on the fifth-day postinjection (p.i.)(Fig. 4c and supplementary Fig. 14).