This inhibition of EGFR driven LDs did not impact the ability of ZIKV or HSV-1 to enter astrocytes, as evidenced by the comparisons of PCR results for 6-hour time points for both viruses as well as immunofluorescent staining of ZIKV and HSV-1 proteins in astrocytes (Fig. 8a–c and Supplementary Fig. 8B); however viral replication was enhanced by as much as 26 and 24-fold at 24 h post infection, and 2 and 24-fold at 48 h post-infection with ZIKV and HSV-1 respectively. Here, EGFR is linked to infection.