MAFF and brain neoplasm: An increase in MAFF under hypoxia was also observed in ovarian, lung, liver, and brain tumor cell lines while MAFG and NRF2 expression was unchanged, indicating that hypoxia induction of MAFF is not cancer type specific but is mediated by a hypoxia-inducible factor common to many cell lines such as HIF (Supplementary Fig. 2e and f).