Multiple regression analysis with the regard of diabetic foot presence (DFS) compared to healthy control subjects showed a significant negative association between diabetic foot and serum levels of omentin (B = − 0.56; p < 0.0005) and a positive association between diabetic foot and hypertension (B = 3.96; p = 0.01) (see Table 3). The gene discussed is ITLN1; the disease is hypertensive disorder.