Likewise, it has been reported that plasma levels of IL-10 and TGFβ are higher in DR-TB than in DS-TB patients, and recent reports have shown that extensively Drug-resistant tuberculosis (XDR-TB) patients with failed anti-TB therapy had increased the frequency of Treg compared to DS-TB (Li et al. 2015; Davids et al. 2018). The gene discussed is TGFB1; the disease is tuberculosis.