The expression of MARK1, PGAP1, KITLG, and CRIP1 genes in four NPC cell lines (CNE1, HNE3, 5–8 F, and HK-1) and normal human immortalized nasopharynx cell line (NP69) were measured via qRT-PCR. The gene discussed is CRIP1; the disease is nasopharyngeal carcinoma.