ACE and angina pectoris: Patients in whom anginal symptoms resolved had a similar rate of 5-year death to patients without angina, despite the poor prognosis associated with angina at baseline.2,3,18,19 Regression of symptoms could be explained by a less progressive atheromatous disease, stabilized by the use of secondary prevention drugs such as statins and angiotensin-converting enzyme inhibitors, allowing an eventless collateral development or adaptation.