CFHR1 and age-related macular degeneration: Interestingly, rs148235292 (FHR-1.1) is in LD (r2 = 0.94) with rs6677604, the tag variant for the CFHR3-CFHR1 deletion, and rs10922108 (FHR-4A.3) is in LD (r2 = 1) with the AMD GWAS 1.1 top variant rs10922109 (Table 3, Table S12).