LGALS1 and metastatic malignant neoplasm in the lymph nodes: We classified the GAL-1 IHC scores as positive and negative using Receiver Operating Curve (ROC) statistics, and observed a significantly higher lymph node metastasis rate in the GAL-1 positive group (64/86) compared with that in the GAL-1 negative group (7/41) (P < 0.01; Figure 1G).