Consequently, the conclusions of many studies indicated an only transient increase of aPL antibodies due to COVID-19; the high proportion of positive LAC levels and discussions about aPL antibody formation after viral infections therefore lead to the need for additional investigation aimed at comparing the aPL antibody composition of LAC, aCL, and anti-β2GPI in COVID-19 with other viral infections. The gene discussed is ACLY; the disease is COVID-19.