CASP3 and neuroblastoma: In the following neuroblastoma cell lines, SK-N-SH, IMR-32, NUB-6 and LAN-1, CBD and ∆9-THC treatment induced antitumorigenic activity by decreasing cell viability and invasiveness, arrest of the cell cycle at the G1/G0 phase and an increase in activated caspase-3, albeit CBD was more potent in these effects when compared to ∆9-THC (Fisher et al. 2016).