DKK1 and myopia: As shown in Figure 1A, the levels of DKK-1 were significantly lower in the high myopia group (median = 324.25 pg/mL, range = 42.2–978.79 pg/mL) in comparison with those in moderate myopia groups (496.67 pg/mL, 130.23–1517.74 pg/mL; P < 0.001, 1-way ANOVA) and non-myopic controls (924.86 pg/mL, 400.08–1799.36 pg/mL; P < 0.001, 1-way ANOVA).