APC and myopia: In a form deprivation (FD) myopia mouse model that reflects the progression of myopia in humans15 and a nonsense mutation of APC gene (APCMin) mouse that developed myopia shift after birth,16 we find that inhibition of the canonical Wnt pathway by niclosamide results in alleviated myopia development, revealing therapeutic Wnt inhibition as a potential treatment for myopia in humans.