Higher levels of the inflammatory cytokines such as interferon gamma (INF-γ), colony-stimulating factors (CSF), IL-1, IL-4, IL-17A, IL-6, IL-13, IL-12 [54], IL-23 [55], IL-27 [56], transforming growth factor beta 1 (TGF-β1), T helper 2 (Th2) cytokine, and the chemotaxis monocyte chemoattractant protein 1 (MCP-1) were detected in scleroderma patients. The gene discussed is CCL2; the disease is scleroderma.