In terms of the mechanism, SCH alleviates asthma by promoting the production of Nrf2 and HO-1, while reducing the levels of NF-κB and IKKα and increasing the level of IκBα, indicating that SCH inhibits airway inflammation by restraining NF-κB but promoting the activation of the Nrf2 pathway. This evidence concerns the gene NFKB1 and asthma.