Interestingly, both BECN1 and LC3B gene expressions from patients with endometriosis treated with COC were found to be significantly lower in endometrium than in endometriotic cyst; however, no significant difference in gene expression was detected when comparing endometriotic cyst and endometrium in patients with untreated endometriosis (Table 5). This evidence concerns the gene MAP1LC3B and endometriosis.