CD8A and neoplasm: In addition, it has been reported that B cell infiltration in KIRC can prolong the cancer-specific survival [31], CD8 + T cell infiltration prolonged the OS outcomes of KIRC patients [32], and upregulation of the abundance of neutrophils was associated with a favorable prognosis of KIRC patients [33], while dendritic cells can effectively inhibit tumor recurrence and metastasis [34].