Very recently, we showed that the inhibition of BMI1 proteins not only helped to eliminate cancer stem cells, but also activated tumor‐intrinsic immune responses by stimulating STING‐IRF3 signaling.[6b] MOC1 cells were derived from 4NQO‐induced HNSCC through multiple passaging in vitro. This evidence concerns the gene BMI1 and head and neck squamous cell carcinoma.