AFP and obesity due to melanocortin 4 receptor deficiency: Similar results in a routine health screening of 56,178 subjects found that values of STK1p level in different liver diseases, including precarcinomas (moderate/severe fatty liver, HBV infection, obesity, HC, etc.)were increased significantly (p < 0.0001) in the following order: health-disease-free (0.38 pM), followed by HBV/obesity/moderate to severe fatty liver (0.54–0.69 pM) and HC (0.96), while AFP and CEA did not (p > 0.05) [13].