Moreover, its overexpression decreased the expression of mesenchymal markers (vimentin and N-cadherin) and the master regulator of EMT (Snail) and enhanced the manifestation of epithelial cell markers (E-cadherin and FSP1), which suggested the upregulation of miR-373 repressed the loss of epithelial functions and acquirement of mesenchymal features, and therefore inhibited the progression of EMT of PCa cells. The gene discussed is CDH2; the disease is posterior cortical atrophy.