Another study indicated that quercetin might treat hyperlipidemia by promoting PPARγ and liver X receptor α (LXRα) expressions to upregulate ATP-binding cassette transporter A1 (ABCA1) genes and increasing cholesterol efflux from THP-1 macrophages in human acute monocytic leukemia cells [104]. The gene discussed is ABCA1; the disease is hyperlipidemia.