LCN2 is critical for the inflammation in retinal degeneration [34], ocular disease [35], intestinal tract [16, 36], ischemic stroke [37], psoriasis [38], cardiovascular diseases [39], alcoholic steatohepatitis [40, 41], nonalcoholic steatohepatitis (NASH) [42], muscle-skeletal disorders [43], and lung infection [44]. Here, LCN2 is linked to skeletal muscle disorder.