C1R and neoplasm: The network visualization of the pathways and related genes showed that FLNC, PLAU, WNT5A, THBS1, MSR1, FRMD6, PLAUR, MMP2, DAPK3, AKT3, THBS2, TUBB2B, GPC1, MMP1, WWTR1, PDGFRA, RASSF2, THBS3, C1R, MRC2, COMP, and ITGA11 were the hub genes involved in these cancer or tumor microenvironment-related pathways (Figure 5(b)).