In the present study, through bioinformatic analysis of the HCMD-EXP00440 database, 5 lncRNAs (CATIP-AS2, TTC3-AS1, LINC01993, LINC01564, and LINC02015) and 11 specific TFs (POU5F1, CUX2, TBX19, POU2F1, PLAG1, ZFP57, LMX1A, MZF1, BACH1, ONECUT1, and IRF9) were identified to be significantly upregulated in metastatic tumor samples (n = 21), compared with primary tumor samples (n = 351). The gene discussed is IRF9; the disease is neoplasm.