IGKV1D-22 and nasopharyngeal carcinoma: Interestingly, the results indicated that as low as 1 μg/ml S100A8/A9 added to the lower chamber culture medium could already significantly drive the migration and invasion towards S100A8/A9 stimulation for all the three NPC cell lines including CNE1, CNE2, and 6-10B (Figures 2(a)–2(c)).