To shed more light on the mechanisms running in the background of our observation, i.e., overexpression of CD44v8-10 in colon polyps, we tested expression levels of RNA binding proteins ESRP-1 and ESRP-2 that are known to control ASP of CD44 in prostate epithelial cells [34] (Figure 6D). The gene discussed is ESRP2; the disease is intestinal disorder.